HCID 23433656, compound → HCID 23433458, compound

Participants

Reaction Steps

This compound was prepared according to General Method 3 (EXAMPLE 16) from 2-amino-5-fluorofluorene (structure 15, where R2, R4-6=H, R3=F, X=CH2) (360 mg, 1.72 mmol) to 125 mg (26%) of Compound 126 as a light brown solid. Data for Compound 126: Rf=0.63 (silca gel, hexane/EtOAc, 3:1); 1H NMR (400 MHz, acetone-d6): 7.55 (s, 1H), 7.25 (d, J=7.3, 1H), 7.12 (m, 1H), 7.02 (d, J=10, 10, 1H) 6.73 (s, 1H), 5.39 (s, 1H), 3.81 (s, 2H), 2.87 (s, 3H), 1.28 (s, 6H).

Provenance & Evidence