Potassium Carbonate → 1,3,5-Triiodo-2,4,6-trihydroxymethylbenzene

HRID 1280117Notes

Reaction equation

HRID 1280117 reaction equation
[I:1][C:2]1[C:7]([CH2:8][O:9]C(=O)C)=[C:6]([I:13])[C:5]([CH2:14][O:15]C(=O)C)=[C:4]([I:19])[C:3]=1[CH2:20][O:21]C(=O)C.C([O-])([O-])=O.[K+].[K+]>CO>[I:1][C:2]1[C:3]([CH2:20][OH:21])=[C:4]([I:19])[C:5]([CH2:14][OH:15])=[C:6]([I:13])[C:7]=1[CH2:8][OH:9]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 235425991,3,5-Triiodo-2,4,6-triacetoxymethylbenzene

Product 1

HCID 206936271,3,5-Triiodo-2,4,6-trihydroxymethylbenzene

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1,3,5-Triiodo-2,4,6-triacetoxymethylbenzene (9.3 g, 13.8 mmol) was suspended in methanol (120 ml) and K2CO3 (0.32 g, 2.3 mmol) was added. The mixture was stirred at ambient temperature for 16 h, and, after neutralization of the solution with 2M aqueous HCl, the organic solvent was evaporated. The residue was suspended in water and the white solid was collected by filtration and washed with water, methanol and ether. Yield: 7.1 g (94%).

Workup

  1. customafter neutralization of the solution with 2M aqueous HCl, the organic solvent was evaporated
  2. filtrationthe white solid was collected by filtration
  3. washwashed with water, methanol and ether

Sources & evidence

ORD record
ord-832b65eb80bc4de8bf018f794d127336
Source dataset
uspto-grants-2002_09
Patent number
US06448442B1

Reaction notes

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