反应详情

2,3,4-Triacetoxybutanoyl chloride (39.9 g, 0.142 mol), prepared according to the liteature procedure Glattfeld, J. and Kribben, B., J.Am. Chem. Soc. 61 (1939) 1720) was mixed with lithium bromide (30.9 g, 0.356 mol) in methylene chloride (400 ml) and stirred at ambient temperature for 24 h. The mixture was filtered, the solid was washed with additional methylene chloride (50 ml) and the filtrate was evaporated at ambient temperature to give 45 g (97%) of the crude product as an oil.

1. filtrationThe mixture was filtered
2. washthe solid was washed with additional methylene chloride (50 ml)
3. customthe filtrate was evaporated at ambient temperature