Hydroxyamine hydrochloride → HCID 178518587, compound

Participants

Reaction Steps

A stirred mixture of 6.34 g (0.02 mole) of 1-(2-benzoyl-4-chlorophenyl)-3-isopropylurea and 4.17 g (0.06 mole) of hydroxylamine hydrochloride in 100 ml of ethanol was refluxed for 48 hr, and then cooled. The suspended crystals were collected on a filter, washed with alcohol, and then dried in air to give 4.60 g (84%) of 6-chloro-4-phenyl-(2(1H)-quinazolinone 3-oxide as yellow crystals, mp 267°-269° (dec.).

Provenance & Evidence