Cvt-2738 → N-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-indan-2-yloxypropyl)piperazinyl]acetamide

Participants

Reaction Steps

To a solution of 6 (0.43 g, 2.3 mmol) in ethanol(4 ml) was added 5 (0.405 g, 1.64 mmol). The solution was heated to reflux and stirred for 24 h. Upon completion the solution was concentrated in vacuo and purified using Prep TLC (10:1, DCM:MeOH) to yield 7. Mass Spectrum (M+1)=438.36.

Provenance & Evidence