Isopropanol → HCID 10115961, compound

HRID 1280426Notes

Reaction equation

HRID 1280426 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:32])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH:19]([OH:31])[CH2:20][O:21][CH:22]2[CH2:30][C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH2:23]2)[CH2:14][CH2:13]1.[CH3:33][CH:34](O)C>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([CH3:1])[C:3]=1[NH:9][C:10](=[O:32])[CH2:11][N:12]1[CH2:13][CH2:14][N:15]([CH2:18][CH:19]([OH:31])[CH2:20][O:21][CH2:22][C:23]2[CH:24]=[CH:25][C:26]([CH2:27][CH2:28][CH2:29][CH3:30])=[CH:34][CH:33]=2)[CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 3776IsopropanolHCID 10181578N-(2,6-dimethylphenyl)-2-[4-(2-hydroxy-3-indan-2-yloxypropyl)piperazinyl]acetamide

Product 1

HCID 10115961HCID 10115961, compound

Procedure

Compound 24 was prepared in a similar manner to compound 7, substituting the commercially available 4-n-bu-benzylalcohol for 2-propanol in part C. MS (M+1)=468.45

Sources & evidence

ORD record
ord-f164f4fa2fa5437281e7c7559ffb5231
Source dataset
uspto-grants-2002_09
Patent number
US06451798B2

Reaction notes

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