참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | N-[(1R)-2-hydroxy-1-(3-carboxybenzyl)ethyl]acetamide | HCID 69699113 | — |
| 생성물 | (2R)-2-amino-3-(3-carboxyphenyl)-1-propanol hydrochloride | HCID 69885138 | — |
반응 단계
The process is performed as in Example 2, starting with 1.96 g of N-[(1R)-2-hydroxy-1-(3-carboxybenzyl)ethyl]acetamide in 14 cm3 of aqueous 6N hydrochloric acid heated at a temperature in the region of 100° C. for 17 hours. After an identical work-up, 2.16 g of (2R)-2-amino-3-(3-carboxyphenyl)-1-propanol hydrochloride are obtained in the form of a white solid melting at 194° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06451821B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_09 |
|---|
| ORD ID | ord-f21d1874b27444aab31b1c0d24c2f79a |
|---|
| 출처 메모 | uspto-grants-2002_09 |
|---|
