Pyrrolidine → HCID 18188148, compound

HRID 1280692Notes

Reaction equation

HRID 1280692 reaction equation
[CH2:1]([N:8]([CH3:25])[C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH3:21])([CH2:19][OH:20])[C:16]([OH:18])=O)=[CH:11][C:10]=1[N+:22]([O-:24])=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:26]1[CH2:30][CH2:29][CH2:28][CH2:27]1>>[CH2:1]([N:8]([CH3:25])[C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH3:21])([CH2:19][OH:20])[C:16]([N:26]2[CH2:30][CH2:29][CH2:28][CH2:27]2)=[O:18])=[CH:11][C:10]=1[N+:22]([O-:24])=[O:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 18188190HCID 18188190, compound

Product 1

HCID 18188148HCID 18188148, compound

Procedure

Prepared analogously to Example 1e from 2-[4-(N-benzyl-methylamino)-3-nitro-phenyl]-3-hydroxy-2-methyl-propionic acid and pyrrolidine.

Sources & evidence

ORD record
ord-91457c056ba5464da4716353d7e3010b
Source dataset
uspto-grants-2002_09
Patent number
US06451832B2

Reaction notes

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