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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1280708Generated: October 29, 2026

(RS)-4-(Pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid → (RS)-4-[1-(2-Indan-2-yl-ethyl)-pyrrolidine-3-sulfonyl]-phenol

https://huagongshe.com/reaction/1280708

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(RS)-4-(Pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acidHCID 18425771—
ReactantToluene-4-sulfonic acid 2-indan-2-yl-ethyl esterHCID 86584021—
Product(RS)-4-[1-(2-Indan-2-yl-ethyl)-pyrrolidine-3-sulfonyl]-phenolHCID 18425794—

Reaction Steps

The title compound, MS: m/e=372.3 (M+H+) was prepared from (RS)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and toluene-4-sulfonic acid 2-indan-2-yl-ethyl ester. Toluene-4-sulfonic acid 2-indan-2-yl-ethyl ester is a known compound and has been prepared as described in U.S. Pat. No. 3,984,407.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06451819B2
Source datasetuspto-grants-2002_09
ORD IDord-e7884884ed074d8f9460c0a98e311742
Source noteuspto-grants-2002_09