2-(2-chloro-ethyl)-2,3-dihydro-1H-isoindole → (RS)-4-{1-[2-(1,3-Dihydro-isoindol-2-yl)-ethyl]-pyrrolidine-3-sulfonyl)-phenol hydrochloride

Participants

Reaction Steps

The title compound, MS: m/e=373.3 (M+H+) was prepared from (RS)-4-(pyrrolidine-3-sulfonyl)-phenol trifluoroacetic acid salt and 2-(2-chloro-ethyl)-2,3-dihydro-1H-isoindole. 2-(2-Chloro-ethyl)-2,3-dihydro-1H-isoindole is a known compound and has been prepared as described in the following reference: G. Shoeb; J. Pharm. Sci.; 51; 1962; 469-471.

Provenance & Evidence