Hydrazine hydrate (1:1) → HCID 18426078, compound

HRID 1280790Notes

Reaction equation

HRID 1280790 reaction equation
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]([CH:9]2[C:17](=O)[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]2=O)=O)=[CH:5][CH:4]=1.O.[NH2:23][NH2:24]>>[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]2[C:9]3[CH2:17][C:16]4[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=4)[C:10]=3[NH:23][N:24]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 27367222-(4-Methoxybenzoyl)indan-1,3-dione

Product 1

HCID 18426078HCID 18426078, compound

Procedure

A mixture of 2-(4-methoxybenzoyl)indan-1,3-dione (1.4 g, prepared by a modification of the method disclosed in J. Het. Chem. 8, 855-859 (1971)), and hydrazine hydrate (15 ml) was boiled under reflux for 24 hours. The mixture was cooled, poured into ice-water and the solid which precipitated was collected by filtration, washed with absolute ethanol and dried to give 3-(4-methoxyphenyl)-1,4-dihydroindeno[1,2-c]pyrazole, m.p. 247° C.

Workup

  1. customprepared by a modification of the method
  2. temperatureunder reflux for 24 hours
  3. temperatureThe mixture was cooled
  4. customthe solid which precipitated
  5. filtrationwas collected by filtration
  6. washwashed with absolute ethanol
  7. customdried

Sources & evidence

ORD record
ord-8ce6f2fc4c2a449c9ac9b18fb5a552a4
Source dataset
uspto-grants-2002_09
Patent number
US06451834B1

Reaction notes

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