tert-Butyl carbazate → HCID 56980124, compound

HRID 1280792Notes

Reaction equation

HRID 1280792 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=O)[CH2:7][CH2:6]2.[C:13]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])(=[O:16])[NH:14][NH2:15]>C(O)C.C(O)(=O)C>[C:18]([O:17][C:13]([NH:14][N:15]=[C:8]1[C:9]2[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:11][CH:10]=2)[CH2:6][CH2:7]1)=[O:16])([CH3:21])([CH3:20])[CH3:19]

Participants

5

Reactant 2

HCID 70091tert-Butyl carbazateHCID 787875-Methoxyindan-1-one

Product 1

HCID 56980124HCID 56980124, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 702EthanolSolvent

Procedure

A solution of 5-methoxyindan-1-one (5.46 g) and tert-butyl carbazate (4.45 g) in ethanol (100 ml) and glacial acetic acid (1 drop) was stirred and boiled under reflux for 2 hours. The volume was reduced by half under reduced pressure and the solid which crystallized was collected by filtration to give 5-methoxyindan-1-one tert-butyloxycarbonylhydrazone.

Workup

  1. temperatureunder reflux for 2 hours
  2. customthe solid which crystallized
  3. filtrationwas collected by filtration

Sources & evidence

ORD record
ord-ef1cc3033e1b4cc0bdd499caa7ec3f76
Source dataset
uspto-grants-2002_09
Patent number
US06451834B1

Reaction notes

Loading…