HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 4-[[N-(2-amino-5-trifluoromethylbenzoyl)glycyl]aminomethyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-[{(N-(2-Amino-4,5-difluorobenzoyl)glycyl)amino}methyl]piperidine | HCID 18426176 | — |
| Reactant | 4-[{(N-(2-(tert-butoxycarbonylamino)-5-trifluoromethylbenzoyl)glycyl)amino}methyl]piperidine | HCID 18426225 | — |
| Reactant | 4-[{N-(2-(tert-butoxycarbonylamino)-5-trifluoromethoxybenzoyl)glycyl}aminomethyl]piperidine | HCID 18426235 | — |
| Product | 4-[[N-(2-amino-5-trifluoromethylbenzoyl)glycyl]aminomethyl]piperidine | HCID 18426227 | — |
Reaction Steps
4-[{(N-(2-Amino-4,5-difluorobenzoyl)glycyl)amino}methyl]piperidine, 4-[{N-(2-(tert-Butoxycarbonylamino)-5-trifluoromethoxybenzoyl)glycyl}aminomethyl]piperidine, 4-[{N-(2-(tert-butoxycarbonylamino)-4,5-difluorobenzoyl)glycyl)amino}methyl]piperidine, and 4-[{(N-(2-(tert-butoxycarbonylamino)-5-trifluoromethylbenzoyl)glycyl)amino}methyl]piperidine were also prepared pursuant to the above method using the corresponding reactant, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06451842B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-523888255d644986a5601d4407ac1a9f |
| Source note | uspto-grants-2002_09 |