Hydrochloric Acid → HCID 22664405, compound

HRID 1281071Notes

Reaction equation

HRID 1281071 reaction equation
[F:1][C:2]([F:36])([F:35])[C:3]1[CH:34]=[CH:33][C:6]2=[N:7][N:8]([C:10]3[CH:11]=[C:12]([CH:19]=[C:20]([C:23]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=4[F:32])([CH3:25])[CH3:24])[C:21]=3[OH:22])[CH2:13][CH2:14][C:15]([O:17]C)=[O:16])[N:9]=[C:5]2[CH:4]=1.Cl>[OH-].[Na+]>[F:36][C:2]([F:1])([F:35])[C:3]1[CH:34]=[CH:33][C:6]2=[N:7][N:8]([C:10]3[CH:11]=[C:12]([CH:19]=[C:20]([C:23]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=4[F:32])([CH3:25])[CH3:24])[C:21]=3[OH:22])[CH2:13][CH2:14][C:15]([OH:17])=[O:16])[N:9]=[C:5]2[CH:4]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22664347HCID 22664347, compound

Product 1

HCID 22664405HCID 22664405, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The title compound is prepared by refluxing the compound prepared in Example 50 in aqueous sodium hydroxide solution followed by neutralization with aqueous hydrochloric acid.

Sources & evidence

ORD record
ord-42349882b08c46919d6959ed9f6b77a7
Source dataset
uspto-grants-2002_09
Patent number
US06451887B1

Reaction notes

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