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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281130Generated: November 1, 2026

2-Chloro-5-(chloromethyl)thiophene → 1-(5-Chlorothiophen-2-ylmethyl)-5,6-dichloro2-(4-formylphenyl)benzimidazole

https://huagongshe.com/reaction/1281130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(chloromethyl)thiopheneHCID 583079—
Reactant5,6-Dichloro-2-(4-formylphenyl)benzimidazoleHCID 18426793—
Product1-(5-Chlorothiophen-2-ylmethyl)-5,6-dichloro2-(4-formylphenyl)benzimidazoleHCID 18426858—

Reaction Steps

1-(5-Chlorothiophen-2-ylmethyl)-5,6-dichloro2-(4-formylphenyl)benzimidazole was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and 2-chloro-5-chloromethylthiophene by following General Procedure 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06452014B1
Source datasetuspto-grants-2002_09
ORD IDord-75e41803c6164cb7bac3f252ca086eda
Source noteuspto-grants-2002_09