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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281131Generated: November 2, 2026

2-(Chloromethyl)quinoline → 5,6-Dichloro-2-(4-formylphenyl)-1-(quinolin-2-ylmethyl)benzimidazole

https://huagongshe.com/reaction/1281131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)quinolineHCID 20394—
Reactant5,6-Dichloro-2-(4-formylphenyl)benzimidazoleHCID 18426793—
Product5,6-Dichloro-2-(4-formylphenyl)-1-(quinolin-2-ylmethyl)benzimidazoleHCID 18426829—

Reaction Steps

5,6-dichloro-2-(4-formylphenyl)-1-(quinolin-2-ylmethyl)benzimidazole was prepared from 5,6-dichloro-2-(4-formylphenyl)benzimidazole obtained in Example 13 and 2-chloromethylquinoline by following General Procedure 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06452014B1
Source datasetuspto-grants-2002_09
ORD IDord-f98b774695cc4caaae8088650275425c
Source noteuspto-grants-2002_09