Methyl iodide → HCID 470063, compound

HRID 1281657Notes

Reaction equation

[CH2:1]([S:8][C:9]1[N:13]([C@H:14]2[O:20][C@H:19]([CH2:21][OH:22])[C@H:17]([OH:18])[C@@H:15]2[OH:16])[C:12]2[CH:23]=[C:24]([Cl:28])[C:25]([Cl:27])=[CH:26][C:11]=2[N:10]=1)C1C=CC=CC=1.CI>>[Cl:27][C:25]1[C:24]([Cl:28])=[CH:23][C:12]2[N:13]([C@@H:14]3[O:20][C@@H:19]([CH2:21][OH:22])[C@@H:17]([OH:18])[C@H:15]3[OH:16])[C:9]([S:8][CH3:1])=[N:10][C:11]=2[CH:26]=1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 10694437HCID 10694437, compound

Product 1

HCID 470063HCID 470063, compound

Procedure

The procedure is the same as that described for compound 11b, except that methyl iodide (0.06 mL, 1.0 mmole) was used instead of benzylbromide. The TLC (co-spots solvent system 1) and proton spectrum were identical to that obtained for compound 12a. Yield: 142 mg (39%) as white crystals. Mp: 204-206° C. Anal. (C13H14O4N2Cl2S) C, H, N.

Sources & evidence

ORD record: ord-feb0ee85f57e462887bcc09524364f0d
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06455506B1

Reaction notes

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