HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 470063, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | (2S,3S,4R,5R)-2-(2-benzylsulfanyl-5,6-dichloro-benzimidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol | HCID 10694437 | — |
| Product | HCID 470063 | HCID 470063 | — |
Reaction Steps
The procedure is the same as that described for compound 11b, except that methyl iodide (0.06 mL, 1.0 mmole) was used instead of benzylbromide. The TLC (co-spots solvent system 1) and proton spectrum were identical to that obtained for compound 12a. Yield: 142 mg (39%) as white crystals. Mp: 204-206° C. Anal. (C13H14O4N2Cl2S) C, H, N.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455506B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-feb0ee85f57e462887bcc09524364f0d |
| Source note | uspto-grants-2002_09 |