1,2-Dichloroethane → HCID 70095509, compound

Participants

Reaction Steps

4-(4-Chlorobenzoyl)piperidine (0.2 g) was added to a solution of methyl 3-isobutylsuccinic acid (0.15 g) and EDC (0.25 g) in dichloromethane (10 ml) and the solution was stirred for 18 h, then washed with water (10 ml), aqueous citric acid (10 ml), saturated sodium bicarbonate (10 ml) and brine (10 ml), dried over magnesium sulphate (1 g) and evaporated to give the title compound (0.25 g) as a colourless solid.

Provenance & Evidence