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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1281760Generated: November 2, 2026

1,3,5-Trifluoro-2-nitrobenzene → HCID 18422318, compound

https://huagongshe.com/reaction/1281760

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3,5-Trifluoro-2-nitrobenzeneHCID 67567—
ReactantEthyl 2-amino-1-benzothiophene-3-carboxylateHCID 699464—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 18422318HCID 18422318—

Reaction Steps

In the same manner as in Starting Material Synthesis Example 4 and using ethyl 2-aminobenzo[b]thiophene-3-carboxylate, 2,4,6-trifluoronitrobenzene and dimethyl sulfoxide, ethyl 2-(3,5-difluoro-2-nitroanilino)benzo[b]thiophene-3-carboxylate is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455521B1
Source datasetuspto-grants-2002_09
ORD IDord-a188b08e7cbb41b0a17757ac218c606f
Source noteuspto-grants-2002_09