HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosuccinimide → HCID 18422325, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | HCID 18422149 | HCID 18422149 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | HCID 18422325 | HCID 18422325 | — |
Reaction Steps
3-Fluoro-8-methyl-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine is dissolved in carbon tetrachloride and reacted with 2,2′-azobis(isobutylonitrile) in the presence of N-chlorosuccinimide to give 8-chloromethyl-3-fluoro-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455521B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-0f29812b40ca4401905450bf6a11c400 |
| Source note | uspto-grants-2002_09 |