Diethylamine → HCID 18423395, compound

HRID 1281911Notes

Reaction equation

HRID 1281911 reaction equation
C(O[C:5]1[C:6](=[O:14])[C:7](=[O:13])[C:8]=1[O:9][CH:10]([CH3:12])[CH3:11])(C)C.[CH2:15]([NH:17][CH2:18][CH3:19])[CH3:16]>CCO>[CH2:15]([N:17]([CH2:18][CH3:19])[C:5]1[C:6](=[O:14])[C:7](=[O:13])[C:8]=1[O:9][CH:10]([CH3:11])[CH3:12])[CH3:16]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 1823143,4-Diisopropoxy-3-cyclobutene-1,2-dione

Product 1

HCID 18423395HCID 18423395, compoundYield 93.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 3,4-diisopropoxy-3-cyclobutene-1,2-dione (1.0 g, 5.05 mmol) and diethylamine (549 μl, 5.30 mmol) in EtOH (25 ml) was stirred overnight at room temperature. The solvent was removed in vacuo to give the title compound as a yellow oil (1.0 g). δH (DMSO-d6, 390 K) 5.33-5.27 (1H, m), 3.58 (4H, q, J 7.1 Hz), 1.42 (6H, d, J 6.1 Hz), 1.23 (6H, t, J 7.2 Hz); m/z (ES+, 70 V) 212 (MH+).

Workup

  1. customThe solvent was removed in vacuo

Sources & evidence

ORD record
ord-2fcbbe16fdca4eb3b8fe9ed466d6d3cb
Source dataset
uspto-grants-2002_09
Patent number
US06455539B2

Reaction notes

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