HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-3,5-dimethylisoxazole → 7-Methoxy-2-methoxymethylbenzofuran-4-carboxylic acid (3,5-dimethylisoxazol-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-3,5-dimethylisoxazole | HCID 182040 | — |
| Reactant | HCID 18423641 | HCID 18423641 | — |
| Product | 7-Methoxy-2-methoxymethylbenzofuran-4-carboxylic acid (3,5-dimethylisoxazol-4-yl)-amide | HCID 9862320 | 69.4% |
Reaction Steps
Starting from 7-methoxy-2-methoxymethylbenzofuran-4-carboxylic acid (0.19 g) and 3,5-dimethylisoxazol-4-ylamine (88 mg). Purification by column chromatography on silica eluting with ethyl acetate afforded the title compound as a cream solid (0.18 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455561B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-e4399eb88f1e4dd5b69f17f5a1b2b566 |
| Source note | uspto-grants-2002_09 |