HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,4-Difluorophenyl)piperazine dihydrochloride → N-(1-methyl-1-(4-((4-(2,4-difluorophenyl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,4-Difluorophenyl)piperazine dihydrochloride | HCID 14126745 | — |
| Reactant | N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide | HCID 18423089 | — |
| Product | N-(1-methyl-1-(4-((4-(2,4-difluorophenyl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide hydrochloride | HCID 70037297 | — |
Reaction Steps
By similar reaction and treatment to that in Example 1(5) using 1-(2,4-difluorophenyl)piperazine dihydrochloride instead of phenylpiperazine and N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide instead of N-(4-chloromethylphenylmethyl)acetamide, the title compound was obtained as pale-brown crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455528B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-8d05efb3e4554375b5678f983c67abc3 |
| Source note | uspto-grants-2002_09 |