反应详情

To a suspension of aluminum lithium hydride (570 mg) in tetrahydrofuran (80 ml) was added a solution of methyl 4-acetamidomethylbenzoate (3.1 g) in tetrahydrofuran (20 ml) under ice-cooling. The reaction mixture was stirred at room temperature for 1.5 hr. A saturated aqueous sodium sulfate solution (7 ml) was added at 10° C., and the mixture was stirred at room temperature for 1 hr. The sediment was filtered off and the solvent was evaporated to give the title compound (2.8 g) as a white solid.

1. temperaturecooling
2. stirringthe mixture was stirred at room temperature for 1 hr
3. filtrationThe sediment was filtered off
4. customthe solvent was evaporated