1-(Thiazol-2-yl)piperazine → N-(1-methyl-1-(4-((4-(thiazol-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	1-(Thiazol-2-yl)piperazine	HCID 911806	—
Reactant	N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide	HCID 18423089	—
Product	N-(1-methyl-1-(4-((4-(thiazol-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide	HCID 11717426	—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(thiazol-2-yl)piperazine instead of phenylpiperazine, the title compound was obtained as pale-yellow crystals, m.p.=118-120° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06455528B1
Source dataset	uspto-grants-2002_09
ORD ID	ord-aa88b7b307804a659133df027fa3adcb
Source note	uspto-grants-2002_09