1-(Thiazol-2-yl)piperazine → N-(1-(4-((4-(thiazol-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	1-(Thiazol-2-yl)piperazine	HCID 911806	—
Reactant	N-(1-(4-chloromethylphenyl)ethyl)acetamide	HCID 18423033	—
Product	N-(1-(4-((4-(thiazol-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide	HCID 11493939	—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using N-(1-(4-chloromethylphenyl)ethyl)acetamide obtained in Example 48(3) instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(thiazol-2-yl)piperazine obtained in Example 81(1) instead of phenylpiperazine, the title compound was obtained as white crystals, m.p.=136-137° C.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06455528B1
Source dataset	uspto-grants-2002_09
ORD ID	ord-6f7a131e936a49dbb0d8d3a2c626014e
Source note	uspto-grants-2002_09