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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1282175Generated: November 1, 2026

4-Methoxy-2-(piperazin-1-yl)pyrimidine → HCID 18423049, compound

https://huagongshe.com/reaction/1282175

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-2-(piperazin-1-yl)pyrimidineHCID 11480987—
ReactantN-(1-(4-chloromethylphenyl)-1-methylethyl)acetamideHCID 18423089—
ProductHCID 18423049HCID 18423049—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using N-(1-(4-chloromethylphenyl)-1-methylethyl)acetamide obtained in Example 95(4) instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(4-methoxypyrimidin-2-yl)piperazine obtained in Example 98(2) instead of phenylpiperazine, the title compound was obtained as white crystals, m.p.=160-162° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455528B1
Source datasetuspto-grants-2002_09
ORD IDord-ba238dcffd47408c8c8f5143d4406ca7
Source noteuspto-grants-2002_09