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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1282176Generated: November 1, 2026

4-Methoxy-2-(piperazin-1-yl)pyrimidine → HCID 18423183, compound

https://huagongshe.com/reaction/1282176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxy-2-(piperazin-1-yl)pyrimidineHCID 11480987—
ReactantN-(1-(4-chloromethylphenyl)ethyl)acetamideHCID 18423033—
ProductHCID 18423183HCID 18423183—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using N-(1-(4-chloromethylphenyl)ethyl)acetamide obtained in Example 48(3) instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(4-methoxypyrimidin-2-yl)piperazine obtained in Example 98(2) instead of phenylpiperazine, the title compound was obtained as pale-yellow crystals, m.p.=113-115° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455528B1
Source datasetuspto-grants-2002_09
ORD IDord-3e35d75395624521a7cf5c2a26360229
Source noteuspto-grants-2002_09