反应详情

5 g of 3-(m-trifluoromethylphenyl)-piperidine hydrochloride were dissolved in water and the solution was cooled on an ice bath and was made alkaline with sodium hydroxide. The mixture was extracted with ether and the ether were washed with water, dried over magnesium sulfate and evaporated to dryness under reduced pressure to obtain 4.6 g of 3-(m-trifluoromethylphenyl)-piperidine.

1. temperaturethe solution was cooled on an ice bath
2. extractionThe mixture was extracted with ether
3. washthe ether were washed with water
4. dry with materialdried over magnesium sulfate
5. customevaporated to dryness under reduced pressure