HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-fluoropyridin-2-yl)piperazine → (S)-N-(1-(4-((4-(6-fluoropyridin-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-fluoropyridin-2-yl)piperazine | HCID 3728818 | — |
| Reactant | (S)-N-(1-(4-(Chloromethyl)phenyl)ethyl)acetamide | HCID 53659736 | — |
| Product | (S)-N-(1-(4-((4-(6-fluoropyridin-2-yl)piperazin-1-yl)methyl)phenyl)ethyl)acetamide | HCID 15549973 | — |
Reaction Steps
By similar reaction and treatment to that in Example 1(5) using (S)-N-(1-(4-chloromethylphenyl)ethyl)acetamide instead of N-(4-chloromethylphenylmethyl)acetamide and 1-(6-fluoropyridin-2-yl)piperazine obtained in Example 85(2) instead of phenylpiperazine, the title compound was obtained as a pale-yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455528B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-0880440ed607436aad4505b29f708aa0 |
| Source note | uspto-grants-2002_09 |