1-(6-fluoropyridin-2-yl)piperazine → N-(1-(4-(1-(4-(6-fluoropyridin-2-yl)piperazin-1-yl)ethyl)phenyl)-1-methylethyl)acetamide

Participants

Role	Name	HCID	Charge
Reactant	1-(6-fluoropyridin-2-yl)piperazine	HCID 3728818	—
Reactant	N-(1-(4-(1-chloroethyl)phenyl)-1-methylethyl)acetamide	HCID 18423053	—
Product	N-(1-(4-(1-(4-(6-fluoropyridin-2-yl)piperazin-1-yl)ethyl)phenyl)-1-methylethyl)acetamide	HCID 11509254	—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using 1-(6-fluoropyridin-2-yl)piperazine obtained in Example 85(2) instead of phenylpiperazine and N-(1-(4-(1-chloroethyl)phenyl)-1-methylethyl)acetamide instead of N-(4-chloromethylphenylmethyl)acetamide, the title compound can be obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06455528B1
Source dataset	uspto-grants-2002_09
ORD ID	ord-f8766c8af7ba427184a3ddf8ae84a654
Source note	uspto-grants-2002_09