1,3,5-trimethyl-1H-pyrazol-4-amine → HCID 9901233, compound

HRID 1282214Notes

Reaction equation

HRID 1282214 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]=[C:10]=[S:11].[NH2:12][C:13]1[C:14]([CH3:20])=[N:15][N:16]([CH3:19])[C:17]=1[CH3:18]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10]([NH:12][C:13]1[C:14]([CH3:20])=[N:15][N:16]([CH3:19])[C:17]=1[CH3:18])=[S:11]

Participants

3

Reactant 2

HCID 1616031,3,5-trimethyl-1H-pyrazol-4-amineHCID 37317252-Chloro-6-Methylphenyl Isothiocyanate

Product 1

HCID 9901233HCID 9901233, compoundYield 67%

Procedure

Prepared using Method A from 4.0 g (21.8 mmol) of 2-chloro-6-methyl-phenyl isothiocyanate and 2.7 g (21.8 mmol) of 4-amino-1,3,5-trimethylpyrazole to give 4.5 g of title compound as a white solid (67% yield, m.p. 201-202° C.).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4639d874d1f94592bd62c65824d0e039
Source dataset
uspto-grants-2002_09
Patent number
US06455566B1

Reaction notes

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