反应详情

A solution of 13.82 g (0.09 mol) of dehydrolinalool (II, R1, R2 and R3 =methyl) in 200 ml of methyl tert.butyl ether was added to 28.35 g of Zeocat® Z6-05-02 and stirred for 30 min. The reaction mixture was evaporated (40° C., 300 mbar) and the resulting solid was subjected to microwave irradiation (600 W power for 4 s). The product was separated from the solid by dissolving in 300 ml acetone and evaporating the solvent in vacuo. The crude 2-ethinyl-tetrahydro-2,6,6-trimethylpyran was obtained in 13.30 g (96.2%) yield as yellowish liquid.

1. customThe reaction mixture was evaporated (40° C., 300 mbar)
2. customthe resulting solid was subjected to microwave irradiation (600 W power for 4 s)
3. customThe product was separated from the solid
4. dissolutionby dissolving in 300 ml acetone
5. customevaporating the solvent in vacuo