HCID 18761594, compound → HCID 86588385, compound

Participants

Reaction Steps

Employing the same general procedure as for the preparation of 2-tert-butyl-5-ethynyl-1-[(4′-methyl)phenoxy]benzene (Compound W), 40 mg (0.1 mmol) 2-tert-butyl-5-trimethylsilanylethynyl-1-[(4′-ethyl)phenoxy]benzene (Compound V) was converted into the title compound using 4.3 mg (0.03 mmol) of potassium carbonate, 3 mL of methanol and 1 mL of dichloromethane. Purification by flash chromatography (silica, 100% hexane) gave the title compound as a clear, yellow oil.

Provenance & Evidence