1-Iodopropane → HCID 70164329, compound

HRID 1282377Notes

Reaction equation

[N+:1]([C:4]1[CH:24]=[CH:23][C:7]([C:8]([C:10]2[N:14]([CH3:15])[C:13]([CH2:16][C:17]([O:19]CC)=[O:18])=[CH:12][C:11]=2[CH3:22])=[O:9])=[CH:6][CH:5]=1)([O-:3])=[O:2].C(I)CC>>[CH2:16]([C:13]1[N:14]([CH3:15])[C:10]([C:8](=[O:9])[C:7]2[CH:23]=[CH:24][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)=[C:11]([CH3:22])[CH:12]=1)[CH3:17].[CH2:13]([CH2:16][C:17]([O-:19])=[O:18])[CH2:12][CH3:11]

Participants

Reactant 2

HCID 336431-Iodopropane

HCID 18424318HCID 18424318, compound

Product 1

HCID 70164329HCID 70164329, compound

Procedure

The alkylation procedure of Example 77A is performed upon ethyl 5-(p-nitrobenzoyl)-1,4-dimethylpyrrole-2-acetate (from Example 85), using an equivalent quantity of n-propyl iodide instead of methyl iodide used in Example 77A to yield ethyl 5-(p-nitrobenzoyl)-1,4-dimethylpyrrole-2-(α-n-propyl)-acetate.

Sources & evidence

ORD record: ord-337619663f494204940ed24e6e6ad7af
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06455703B2

Reaction notes

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