Chloropentafluorobenzene → HCID 178505971, compound

HRID 1282393Notes

Reaction equation

HRID 1282393 reaction equation
Cl[C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[F:12].C([Mg:16][Br:17])(C)C>CCOCC>[F:8][C:7]1[C:2]([Mg:16][Br:17])=[C:3]([F:12])[C:4]([F:11])=[C:5]([F:10])[C:6]=1[F:9]

Participants

4

Reactant 2

HCID 9579ChloropentafluorobenzeneHCID 178418365HCID 178418365, compound

Product 1

HCID 178505971HCID 178505971, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
60 °C

Procedure

In a drybox, 31.45 g of chloropentafluorobenzene prepared as in Example 21 above (0.155 mole) and 64.42 g of a 2 molar ether solution of isopropylmagnesium bromide (iPrMgBr) (0.141 mole) are charged to a Fisher Porter reactor and heated to 60° C. for 4.5 hours. Pentafluorophenylmagnesium bromide is formed.

Workup

  1. additionare charged to a Fisher Porter reactor

Sources & evidence

ORD record
ord-7ac04129fedb4bda811564056a01a77e
Source dataset
uspto-grants-2002_09
Patent number
US06455718B1

Reaction notes

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