Methyl iodide → HCID 23468998, compound

HRID 128240Notes

Reaction equation

HRID 128240 reaction equation
[CH3:1][I:2].[CH:3]1([N:9]2[CH:13]=[CH:12][CH:11]=[C:10]2[CH2:14][N:15]([CH3:17])[CH3:16])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1>CCOCC>[I-:2].[CH:3]1([N:9]2[CH:13]=[CH:12][CH:11]=[C:10]2[CH2:14][N+:15]([CH3:1])([CH3:17])[CH3:16])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 23469001HCID 23469001, compound

Product 1

HCID 23468998HCID 23468998, compoundYield 86.3%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

A solution of methyl iodide (3.55 g) in dry ether (20 ml) was added dropwise to a stirred solution of 1-cyclohexyl-2-dimethylaminomethylpyrrole (4.12 g) in dry ether (50 ml) at 5°. The resulting mixture was stirred at room temperature for 5 hours and then allowed to stand overnight. The solid was filtered off, washed with ether and dried to give [1-cyclohexyl-pyrrol-2-yl]methyl trimethylammonium iodide (6.0 g), m.p.>250° (darkening ca. 190°).

Workup

  1. waitto stand overnight
  2. filtrationThe solid was filtered off
  3. washwashed with ether
  4. customdried

Sources & evidence

ORD record
ord-8c65ea0264b74bee8b618409e51a4ba0
Source dataset
uspto-grants-1981_03
Patent number
US04259345

Reaction notes

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