HCID 18424406, compound → HCID 18424397, compound

Participants

Reaction Steps

An amount (50 mg) of 5-fluoro-4-fluoromethyl-4-(4-trifluoromethylphenoxy)-N-propyl-2-pentynamide was dissolved in o-dichlorobenzene (5 ml) and the solution was heated under reflux for 3.5 hours. The reaction mixture was concentrated under reduced pressure and the resulting residue was subjected to silica gel column chromatography (eluent; hexane/ethyl acetate=3/1) to give the titled compound (31 mg).

Provenance & Evidence