HRID1282483

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7404

Benzenesulfonyl chloride, 4-nitro-

C6H4ClNO4S

结构：NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

HCID7010557

FMOC-LYS-OH

C21H24N2O4

PRODUCTS

生成物

结构：O=C(N[C@@H](CCCCNS(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

HCID14258337

未命名化合物

收率 89%

PROCEDURE

实验过程

Nα-(9-fluorenylmethoxycarbonyl)-L-lysine was reacted with 4-nitrobenzenesulfonyl chloride under the conditions used in example 2 giving 89% of the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-00ed482467af48cb8087238cd2798af7
来源数据集: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06455587B1
来源说明: uspto-grants-2002_09

反应 SMILES

[CH:1]1[C:13]2[CH:12]([CH2:14][O:15][C:16]([NH:18][C@H:19]([C:25]([OH:27])=[O:26])[CH2:20][CH2:21][CH2:22][CH2:23][NH2:24])=[O:17])[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][CH:2]=1.[N+:28]([C:31]1[CH:36]=[CH:35][C:34]([S:37](Cl)(=[O:39])=[O:38])=[CH:33][CH:32]=1)([O-:30])=[O:29]>>[N+:28]([C:31]1[CH:32]=[CH:33][C:34]([S:37]([NH:24][CH2:23][CH2:22][CH2:21][CH2:20][C@@H:19]([C:25]([OH:27])=[O:26])[NH:18][C:16]([O:15][CH2:14][CH:12]2[C:11]3[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=3[C:5]3[C:13]2=[CH:1][CH:2]=[CH:3][CH:4]=3)=[O:17])(=[O:39])=[O:38])=[CH:35][CH:36]=1)([O-:30])=[O:29]