Benzenepropanoic acid → HCID 131723508, compound

HRID 1282516Notes

Reaction equation

[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:2]([CH3:4])[CH3:3].[C:27](O)(=[O:36])[CH2:28][CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:27](=[O:36])[CH2:28][CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[CH:2]([CH3:4])[CH3:3]

Participants

Reactant 2

HCID 107Benzenepropanoic acid

HCID 69107391HCID 69107391, compound

Product 1

HCID 131723508HCID 131723508, compoundYield 81%

Procedure

Nα-isobutyl-Nα-(4-nitrobenzenesulfonyl)-L-lysine was reacted with dihydrocinnamic acid under the conditions described in example 86 to yield 81% of the desired product.

Sources & evidence

ORD record: ord-e871ca5ed8c248488adbcc03dc3ae65a
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06455587B1

Reaction notes

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