3-(2-Nitrophenyl)acrylic acid → HCID 86758529, compound

HRID 1282519Notes

Reaction equation

HRID 1282519 reaction equation
[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:2]([CH3:4])[CH3:3].[N+:27]([C:30]1[CH:40]=[CH:39][CH:38]=[CH:37][C:31]=1[CH:32]=[CH:33][C:34](O)=[O:35])([O-:29])=[O:28]>>[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:34](=[O:35])[CH:33]=[CH:32][C:31]1[CH:37]=[CH:38][CH:39]=[CH:40][C:30]=1[N+:27]([O-:29])=[O:28])[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 928203-(2-Nitrophenyl)acrylic acidHCID 69107391HCID 69107391, compound

Product 1

HCID 86758529HCID 86758529, compoundYield 42%

Procedure

Nα-isobutyl-Nα-(4-nitrobenzenesulfonyl)-L-lysine was reacted with 2-nitrocinnamic acid under the conditions described in example 86 to yield 42% of the desired product.

Sources & evidence

ORD record
ord-647a62d1821947c9896b9f9d7cf8fb25
Source dataset
uspto-grants-2002_09
Patent number
US06455587B1

Reaction notes

Loading…