2-Amino-5-methylthiazole → HCID 54697639, compound

HRID 128266Notes

Reaction equation

HRID 128266 reaction equation
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18]([O:20]C)=O.[CH3:22][C:23]1[S:27][C:26]([NH2:28])=[N:25][CH:24]=1>>[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18]([NH:28][C:26]1[S:27][C:23]([CH3:22])=[CH:24][N:25]=1)=[O:20]

Participants

3

Reactant 2

HCID 3517702-Amino-5-methylthiazoleHCID 547072593-carbomethoxy-4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine 1,1-dioxide

Product 1

HCID 54697639HCID 54697639, compoundYield 46%

Procedure

Prepared analogous to Example 1 from methyl 4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 5-methyl-2-thiazolamine with a yield of 46% of theory.

Sources & evidence

ORD record
ord-9c2974965a1d45e1b9f1ac55430f1243
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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