2-Amino-4-methylpyridine → HCID 20158102, compound

Participants

Reaction Steps

1 g of 4-methyl-5-propargyl-6-phenyl-2-pyrone, 1.5 g of hydroxylamine hydrochloride and 3 g of 2-amino-4-methyl-pyridine were heated for 9 hours to 80° C. After the usual working up, there were obtained 0.82 g (77 %) of 1-hydroxy-4-methyl-5-propargyl-6-phenyl-2-pyridone melting at 200° C (Calc.: 5.9 % N, found: 5.8 % N).

Provenance & Evidence