Hydrochloric Acid → HCID 20374426, compound

HRID 1282738Notes

Reaction equation

HRID 1282738 reaction equation
[Br:1][C:2]1[S:6][C:5]2[CH2:7][CH2:8][CH2:9][CH:10]([NH:11]C=O)[C:4]=2[CH:3]=1.[ClH:14]>>[ClH:14].[Br:1][C:2]1[S:6][C:5]2[CH2:7][CH2:8][CH2:9][CH:10]([NH2:11])[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20348981HCID 20348981, compound

Product 1

HCID 20374426HCID 20374426, compound

Procedure

Acid hydrolysis of 2-bromo-N-formyl-4,5,6,7-tetrahydrobenzo[b]thien-4-amine (Example 35) with 1 N hydrochloric acid after refluxing for one hour and evaporating to dryness affords 2-bromo-4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine hydrochloride.

Workup

  1. temperatureafter refluxing for one hour
  2. customevaporating to dryness

Sources & evidence

ORD record
ord-7270f7bde8ad47158ecfd042b7109427
Source dataset
uspto-grants-1976_08
Patent number
US03972895

Reaction notes

Loading…