Hydrochloric Acid → HCID 21520093, compound

HRID 1282773Notes

Reaction equation

HRID 1282773 reaction equation
[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:17]=[C:18]([S:27](=[O:30])(=[O:29])[NH2:28])[C:19]=1[S:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:12]([O:14]CC)=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+].Cl>C(O)C>[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:17]=[C:18]([S:27](=[O:30])(=[O:29])[NH2:28])[C:19]=1[S:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:12]([OH:14])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 21520083HCID 21520083, compound

Product 1

HCID 21520093HCID 21520093, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of ethyl 3-benzylthio-4-phenylthio-5-sulfamylbenzoate (0.35 g), 1 N sodium hydroxide (10 ml), and ethanol (5 ml) is stirred for 10 minutes. The resulting solution is boiled for 2 minutes and is thereafter left for 1 hour to reach room temperature. 1 N hydrochloric acid (10.5 ml) is added to precipitate 3-benzylthio-4-pnenylthio-5-sulfamylbenzoic acid. After collection by filtration and recrystallization from aqueous ethanol the compound is obtained with a melting point of 208° - 209°C.

Workup

  1. waitThe resulting solution is boiled for 2 minutes
  2. waitis thereafter left for 1 hour
  3. customto reach room temperature
  4. customto precipitate 3-benzylthio-4-pnenylthio-5-sulfamylbenzoic acid
  5. customAfter collection
  6. filtrationby filtration and recrystallization from aqueous ethanol the compound
  7. customis obtained with a melting point of 208° - 209°C.

Sources & evidence

ORD record
ord-502119a423024a0eb02bf88cff0052b3
Source dataset
uspto-grants-1976_08
Patent number
US03972886

Reaction notes

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