HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Chloro-6-methylbenzo(b)thiophene-2-carbonyl chloride | HCID 12339862 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Catalyst | Cuprous chloride | HCID 62652 | — |
| Product | Monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonate | HCID 86737645 | — |
Reaction Steps
Prepared analogous to Example 1(a) from 3-chloro-6-methyl-benzo[b] thiophene-2-carboxylic acid chloride (m.p.: 124.5°-126° C.) by hydrolysis with aqueous sodium hydroxide solution and subsequent reaction with sodium hydrogen sulfite in the presence of copper-(I)-chloride as a catalyst.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259336 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-2d39238ad5b24bcd9396a3393a509da8 |
| Source note | uspto-grants-1981_03 |