HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → methyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Methyl 3-{[(ethoxy-carbonyl-methyl)methylamino]sulfonyl}-6-methyl-benzo[b]thiophene-2-carboxylate | HCID 23468714 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | methyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide | HCID 70578267 | 51% |
Reaction Steps
Prepared analogous to Example 1(e) from methyl 3-{[(ethoxy-carbonyl-methyl)methylamino]sulfonyl}-6-methyl-benzo[b]thiophene-2-carboxylate by reaction with sodium methylate in anhydrous methanol with a yield of 51% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259336 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-3c3a31d342464fd0a373292491db0727 |
| Source note | uspto-grants-1981_03 |