2-Amino-4-methylthiazole → HCID 86737649, compound

HRID 128284Notes

Reaction equation

HRID 128284 reaction equation
[CH3:1][N:2]1[C:7]([C:8](OCC)=[O:9])=[C:6]([OH:13])[C:5]2[S:14][C:15]3[CH:20]=[C:19]([CH3:21])[CH:18]=[CH:17][C:16]=3[C:4]=2[S:3]1(=[O:23])=[O:22].[NH2:24][C:25]1[S:26][CH:27]=[C:28]([CH3:30])[N:29]=1>>[CH3:1][N:2]1[C:7]([C:8]([NH:24][C:25]2[S:26][CH:27]=[C:28]([CH3:30])[N:29]=2)=[O:9])=[C:6]([OH:13])[C:5]2[S:14][C:15]3[CH:20]=[C:19]([CH3:21])[CH:18]=[CH:17][C:16]=3[C:4]=2[S:3]1(=[O:22])=[O:23]

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 86737650HCID 86737650, compound

Product 1

HCID 86737649HCID 86737649, compoundYield 40%

Procedure

Prepared analogous to Example 1 from ethyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-4-methyl-thiazole with a yield of 40% of theory.

Sources & evidence

ORD record
ord-3383b2dc9415462fb26452d81dee2fc1
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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