HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 1,2-Dihydro-8-(3-methyl-2-octyl)-10-[2-methyl-4-(piperidino) butyryloxy]-1,5,5-trimethyl-3H,5H-thiopyrano[2,3-c][1] benzopyran hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 2-Methyl-4-piperidin-1-yl-butyric acid hydrochloride | HCID 21152689 | — |
| Reactant | 1,2-dihydro-10-hydroxy-8-(3-methyl-2-octyl)-1,5,5-trimethyl-3H,5H-thiopyrano[2,3-c][1]benzopyran | HCID 21519993 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,2-Dihydro-8-(3-methyl-2-octyl)-10-[2-methyl-4-(piperidino) butyryloxy]-1,5,5-trimethyl-3H,5H-thiopyrano[2,3-c][1] benzopyran hydrochloride | HCID 68132198 | — |
Reaction Steps
1,2-dihydro-10-hydroxy-8-(3-methyl-2-octyl)-1,5,5-trimethyl-3H,5H-thiopyrano[2,3-c][1]benzopyran is reacted with 2-methyl-4-piperidinobutyric acid hydrochloride in methylene chloride in the presence of dicyclohexylcarbodiimide, according to the procedure of Example 28, to produce the desired ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03972880 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-c90d5d1cb408408f9c215597224edb30 |
| Source note | uspto-grants-1976_08 |